Report on Phenylpropanolamine Hydrochloride
نویسندگان
چکیده
منابع مشابه
Simultaneous Estimation of Phenylpropanolamine Hydrochloride and Triprolidine Hydrochloride in Pharmaceutical Preperations by Rp- Hplc Method
A simple and precise reversed phase HPLC method was developed for the stimulation estimation of phenylpropanolamine and triprolidine in tablet formulation. The method was carried out on a shimpack C8 (25 cm x 4.6mm i.d., 5μ) column with a mobile phase consisting of Acetonitrile: phosphate buffer (25mM) of pH 3.0 (35:65v/v) at a flow rate of 1.2ml/min.detection was carried out at 210 nm. The gua...
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Phenylpropanolamine-induced vasculitis and related intracerebral hemorrhage has moved from the spotlight it occupied following its withdrawal from the market at the end of 2000 after the Food and Drug Administration ruled that it was not safe and effective, but the risk from medicines purchased prior to that time and still in the possession of the public can still pose a health hazard. We prese...
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Three patients developed clinical evidence of myocardial injury after acute ingestion of phenylpropanolamine, a sympathomimetic amine found in a large number of decongestant and appetite suppressant formulations. Increases in the serum creatine kinase and MB isoenzyme levels, ventricular arrhythmias, and electrocardiographic repolarisation abnormalities were seen. Excessive catecholamine stimul...
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We describe 2 patients with intracranial hemorrhage after ingestion of diet pills containing phenylpropanolamine (PPA) in combination with caffeine. The first patient had bilateral simultaneous intracerebral hemorrhages, and the second had a subarachnoid hemorrhage. PPA is widely used most often without prescription and causes intracranial hemorrhage more often than has been realized. The mecha...
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Exogenous substances such as the appetite suppressant fenfluramine are known to be causally related to the development of pulmonary arterial hypertension (PAH). In these cases, the clinical course as well as the pulmonary vascular disease pathologically is indistinguishable from idiopathic PAH. Other exogenous substances, such as amphetamines, cocaine, and meta-amphetamines, have been considere...
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ژورنال
عنوان ژورنال: Journal of AOAC INTERNATIONAL
سال: 1954
ISSN: 0095-9111
DOI: 10.1093/jaoac/37.3.683